The purpose of the Religion, Spirituality, and Health Scientific Interest Group (RSH-SIG) is to foster communication, promote collaboration, and facilitate the exchange of information, understanding, and resources among NIH intramural and extramural scientists and staff, their HHS colleagues, universities, theologians, clergy, clinicians, mutual support groups, and the public concerning the impact of religion and spirituality (R/S) on health and health outcomes. Among other objectives, the RSH-SIG will promote the understanding of research on the intersection of R/S and health in order to promote Cura Personalis or “care for the entire person”, including in the areas of prevention, treatment, and recovery from addiction and other diseases/health conditions. The RSH-SIG will hold virtual monthly meetings on the second Tuesday of the month from 2:00–3:00 p.m. Meetings will serve as a forum for discussion of current and future activities occurring at the intersection of R/S and health. The RSH-SIG is open to all persons within the NIH and associated agencies (including the HHS Center for Faith and Opportunity Initiatives/The Partnership Center, SAMHSA, Indian Health Service, Veterans Health Administration, HRSA, etc.) who share an interest in the intersection of R/S and health.